An examination of subgroup classification in irritable bowel syndrome patients over time: a prospective study.

Penny, Kay I, Smith, Graeme D, Steinke, Douglas T, Kinnear, Moira, Penman, Iain and Ramsay, D (2008) An examination of subgroup classification in irritable bowel syndrome patients over time: a prospective study. International Journal of Nursing Studies, 45 (12). pp. 1715-1720. ISSN 0020-7489

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Irritablebowel syndrome (IBS) is a complex functional gastrointestinal disorder which to date remains poorly understood. Therapies for irritablebowel syndrome (IBS) patients are usually aimed at relieving the predominant symptom; however, little evidence exists as to whether or not the predominant symptom changes with time. Nurses are becoming increasingly involved in the assessment and management of IBS patients.

To categorise IBS patients into one of three sub-types, namely diarrhoea-predominant, constipation-predominant and a third group who alternate between the two, and to investigate changes in patient sub-type classification over time.

Observational cohort study.

The general population of the United Kingdom (UK).

A cohort of 494 IBS patients, with a confirmed Rome II classification diagnosis, was recruited in the UK. Patients’ IBS symptoms were recorded throughout a 26-week period. Proportions of individuals in each IBS subgroup were calculated and probabilities of moving from one subgroup to another between consecutive weeks were estimated.

The percentage of patients given an overall subgroupclassification of diarrhoea-predominant IBD (D-IBS) is 40.9%; 58.1% and 1% were classified as belonging to the alternator (A-IBS) and constipation-predominant (C-IBS) subgroups, respectively.

classified as an alternator or as diarrhoea-predominant have a high probability (0.67 and 0.71, respectively) of remaining in the same subgroup; however this probability is lower for constipation-predominant patients (0.35

Item Type: Article
Print ISSN: 0020-7489
Uncontrolled Keywords: Irritable bowel syndrome; subgroup classification; subgroup change ; medical statistics.
University Divisions/Research Centres: The Business School > School of Management
Dewey Decimal Subjects: 600 Technology > 610 Medicine & health > 610.7 Medical education, research & nursing
Library of Congress Subjects: R Medicine > RA Public aspects of medicine
Item ID: 5168
Depositing User: Mr David Main
Date Deposited: 27 Mar 2012 09:28
Last Modified: 19 Nov 2012 15:01

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