Health-related quality of life and symptom classification in patients with irritable bowel syndrome.

Smith, Graeme D, Steinke, Douglas T, Penny, Kay I, Kinnear, Moira and Penman, Iain (2010) Health-related quality of life and symptom classification in patients with irritable bowel syndrome. Journal of nursing and healthcare of chronic illness, 2 (1). pp. 4-12. ISSN 1752-9816

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Background.  Previous research has established that health-related quality of life can be adversely affected by irritable bowel syndrome IBS. Irritable bowel syndrome has been classified to subgroups by predominant bowel symptom: constipation, diarrhoea or alternating between the two. Little is presently known about the specific impact of irritable bowel syndrome on health-related quality of life within disease sub-groups across time.

Aims.  To examine the health-related quality of life in a cohort of individuals with irritable bowel syndrome to explore the association between quality of life and disease subtype classification.

Setting.  The general population of the UK.

Design.  Longitudinal cohort survey was conducted.

Methods.  Individuals with symptoms of irritable bowel syndrome were recruited via a UK-wide newspaper advertisement. The health-related quality of life was measured using a battery of validated questionnaires.

Results.  Data on 494 participants with a Rome II confirmed diagnosis of irritable bowel syndrome were examined. Measurement of generic health-related quality of life revealed lower median scores (poorer quality of life) in anxiety/depression and pain/discomfort domains of health.

Conclusion.  Health-related quality of life is impaired in community based individuals with IBS. Patients appear to fluctuate between sub-groups when irritable bowel syndrome is classified across time. This study suggests that the impact of irritable bowel syndrome may be greatly underestimated.

Item Type: Article
Print ISSN: 1752-9816
Electronic ISSN: 1752-9824
Uncontrolled Keywords: Disease classification; health-related quality of life; Irritable Bowel Syndrome; logistic regression
University Divisions/Research Centres: The Business School > School of Management
Dewey Decimal Subjects: 600 Technology > 610 Medicine & health > 616 Diseases
Library of Congress Subjects: R Medicine > RC Internal medicine
Item ID: 5104
Depositing User: Mr David Main
Date Deposited: 21 Mar 2012 14:34
Last Modified: 13 Dec 2012 11:31

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