Elliott, Lawrie, Glenday, John, Freeman, Laura, Ajeda, Dina, Johnston, Brian, Christie, Morag and Ogston, Simon (2005) Reducing diazepam prescribing for illicit drug users: a randomised control study. Drug and Alcohol Review, 24 (1). pp. 25-31. ISSN 0959-5236Full text not available from this repository.
Illicit drug users undergoing mandatory reductions in prescribed diazepam were randomly allocated to one of two methods of delivering psychological support to help reduce their prescription: a) an enhanced intervention consisting of skills training and reinforcement, and b) a limited intervention where patients initially received skills training and thereafter only advice. Outcome measures at baseline and six-months consisted of daily diazepam dose; reported illicit drug use; Severity of Dependence Scale;
Hospital Anxiety and Depression Scale (HADS); Pittsburgh Sleep Quality Index. Fifty-three of 119 eligible patients agreed to be randomly allocated to the interventions. Those in the enhanced intervention reduced their daily dose of prescribed diazepam from a mean of 27.8mgs to 19.9mgs at six months (5.3% per month) compared with 29.8 mgs to 17.6mgs at six months (7.5%) among those in the limited intervention group. However, there was no statistically significant difference in the reduction
rate between the intervention groups. Approximately 75% of patients in each group suspended their reduction programme. The enhanced intervention group reported a statistically and clinically greater reduction in the mean HADS depression score (10.6 at baseline and 7.7 at follow-up), compared with a rise from 8.9 to 11.2 in the limited intervention group. In conclusion, it is possible to reduce prescribed diazepam among illicit drug users but not at the rate of 10% per month set by the study. The
difficulties of working with this population necessitate a flexible and possibly long-term approach to reducing prescribed benzodiazepines.
|Uncontrolled Keywords:||Benzodiazepine prescribing, Illicit drug users; Drug addicts|
|University Divisions/Research Centres:||Faculty of Health, Life & Social Sciences > School of Nursing, Midwifery and Social Care|
|Dewey Decimal Subjects:||600 Technology > 610 Medicine & health > 615 Pharmacology & therapeutics
300 Social sciences > 360 Social problems & social services > 363 Other social problems & services
600 Technology > 610 Medicine & health > 610 Medicine & health
|Library of Congress Subjects:||R Medicine > RM Therapeutics. Pharmacology|
|Depositing User:||RAE Import|
|Date Deposited:||06 Mar 2008 10:29|
|Last Modified:||08 Feb 2016 10:55|
Actions (login required)